MCLA,2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo(1,2-a)pyrazin-3-onehydrochloride

MCLA,2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo(1,2-a)pyrazin-3-one hydrochloride 2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo(1,2-a)pyrazin-3-one hydrochloride (ABI) is a potent and selective inhibitor of the enzyme toll-like receptor. The drug has been shown to decrease the metabolic rate in experimental models. ABI has also been used as an analog for other compounds to study their effects on redox potentials and reactive species. It is unclear how ABI inhibits protein synthesis by polymerase chain reaction (PCR). One possible mechanism is that it may inhibit the binding of primers to DNA. ABI also inhibits the production of chemokines which are small proteins that stimulate inflammatory responses. This drug can be used in autoimmune diseases such as rheumatoid arthritis and multiple sclerosis. CAS Number 128322-44-1 Product Name 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride IUPAC Name 6-(4-methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3-ol;hydrochloride Molecular Formula C14H14ClN3O2 Molecular Weight 291.73 g/mol InChI InChI=1S/C14H13N3O2.ClH/c1-9-14(18)17-8-12(15-7-13(17)16-9)10-3-5-11(19-2)6-4-10;/h3-8,18H,1-2H3;1H InChI Key KGMPQNFFCUDXSO-UHFFFAOYSA-N SMILES CC1=C(N2C=C(N=CC2=N1)C3=CC=C(C=C3)OC)O.Cl Synonyms 6-(4-methoxyphenyl)-2-methyl-imidazo[1,2-a]pyrazin-3(7H)-one, monohydrochloride Canonical SMILES CC1=NC2=CNC(=CN2C1=O)C3=CC=C(C=C3)OC.Cl Isomeric SMILES CC1=NC2=CNC(=CN2C1=O)C3=CC=C(C=C3)OC.Cl