GlycoDepot
GlycoDepot

Our Services

Welcome to GlycoDepot, where the intricacies of glycobiology intersect with groundbreaking advancements in science. Discover GlycoDepot's leadership in carbohydrate research, dedicated to fueling the development of biopharmaceuticals and glycomedicine. Explore our comprehensive resources and expertise, tailored to propel your research endeavors towards transformative breakthroughs. We work with partners across all verticals of glycoscience services to provide a comprehensive solution to your problem. Need a simple glycan conjugated with a fluorophore or a complicated workflow of biomarker discovery — we can help you succeed. Join us in unlocking the full potential of glycobiology and shaping the future of medicine.

After the genome, transcriptome, and proteome, glycomics is flourishing in its era. Identifying the number, structure, and function of glycans in cell biology, as well as exploring the relationship between saccharides and life, are difficult tasks. However, more advanced technologies have been developed to enable an increasingly comprehensive understanding of the overall position of glycoscience in biology, making it easier to apply glycomics to precision medicine. Here at GlycoDepot we partner with several key players in the industry, providing best-in-class services. Our services are something you can trust — we value your time and effort, and will work with you toward the desired results.

Bioorthogonal antibody-glycan conjugation chemistry
Our Services

Custom glycan synthesis

Need a glycan or oligosaccharide outside the catalog? Share your target structure, specifications, and quantity for project review.

  1. 01

    Custom Glycosylation Service

    GlycoDepot offers tailored glycosylation services for proteins, antibodies, cell membranes, and bacterial membranes to meet your specific requirements.

  2. 02

    Characterization of Glycosylation in Drugs

    GlycoDepot offers characterization services for glycosylation in protein drugs and antibody drugs using techniques such as gas chromatography–mass spectrometry (GC-MS), among others.

  3. 03

    Anti-glycan Antibody Development

    GlycoDepot specializes in the development of anti-glycan monoclonal antibodies and polyclonal antibodies. We warmly welcome customers from around the globe to collaborate with us.

  4. 04

    Glycosylation Inhibitors Development

    GlycoDepot offers development services for natural inhibitors, metabolic inhibitors, substrate analogs, and glycoside primers tailored to your specific requirements.

  5. 05

    Carbohydrate Separation, Purification and Analysis

    Our range of services encompasses the separation, purification, and analysis of various compounds including microbial carbohydrates, plant carbohydrates, glycosaminoglycans, and glycolipids, among others.

  6. 06

    Carbohydrate Metabolism Analysis

    We provide carbohydrate metabolic analysis services tailored to meet customers' analytical requirements for a variety of glycans, including mannitol, mannose, fructose, and more.

  7. 07

    Lipidomics Analysis Services

    Our expert research teams deliver high-quality lipidomics analysis services customized to meet your specific requirements.

  8. 08

    Sialic Acid Analysis Service

    We have devised numerous analysis strategies to cater to customers' requirements for sialic acid analysis in cancer research. We also offer sialyl tumor antigen production services tailored to the specific needs of each customer.

  9. 09

    Lectin Production Service

    GlycoDepot takes pride in providing customizable lectin production services designed to meet our clients' specific requirements, enabling groundbreaking research across various scientific domains.

Selected projects

Custom glycan synthesis case studies

From gram-scale enzymatic synthesis to research standards with analytical documentation, each project starts with a defined target and an agreed scope.

Case 01

N-glycan synthesis at gram scale

Bottom-up assembly through a fully enzymatic route

Project quantities
1–10 g
Specified purity
≥95%
Stereochemical control
Enzymatic

The brief

The project called for gram-scale Asn-linked N-glycans across multiple glycosylation patterns, with defined structures and a purity specification of at least 95%.

Our approach

A bottom-up, fully enzymatic synthesis strategy used the selectivity of glycosyltransferases to control glycosidic bond formation and achieve high stereochemical control during assembly.

Project scope

The project scope included both 1 g and 10 g N-glycan requirements. Each target was specified separately to align structure, quantity, and purity with the research program.

Case 02

Custom N-glycan standards

Analytical characterization with confidential structural details

Characterization data
NMR
Mass-spectrometric data
MS
Research standards
Custom

The brief

The requirement was a set of custom N-glycan standards with project-specific structural requirements and supporting analytical documentation for research use.

Our approach

The analytical package included NMR spectra and mass-spectrometric datasets to support characterization of the prepared standards. The scope and documentation were tailored to the individual targets.

Project scope

Molecular structures and ligand identities are withheld from this public summary. Project-specific structures and analytical requirements can be discussed privately with our team.

Case 03

GD2 ganglioside characterization

Proton NMR · Mass spectrometry · HPLC

A GD2-ceramide project with complementary structural and chromatographic characterization.

Proton NMR spectrum (1/3)

GD2 ganglioside characterization · Proton NMR spectrum

GD2 ganglioside characterization: Proton NMR spectrum

The supplied analytical package includes a proton NMR spectrum, a mass spectrum, and an HPLC chromatogram with its integrated peak table. Review the original panels below and discuss the chemical form, quantity, and batch requirements with our team.

Selected project data. These panels are not a certificate for every product or batch. HPLC peak-area percentages are not an absolute purity measurement.

Case 04

Custom Siglec ligand

Proton NMR · Mass spectrometry · HPLC

A custom ligand project supported by NMR, mass-spectrometric, and chromatographic data.

Supplied partial Siglec-ligand structure (1/4)

Custom Siglec ligand · Supplied partial Siglec-ligand structure

Custom Siglec ligand: Supplied partial Siglec-ligand structure

The analytical panels document the supplied project material. Only the supplied partial molecular drawing is shown. The full ligand identity remains confidential. These data do not establish binding affinity or biological activity, which require separate evaluation.

Selected project data. These panels are not a certificate for every product or batch. HPLC peak-area percentages are not an absolute purity measurement.

Case 05

N-glycan standard panel

Proton NMR · Structure-defined research standards

A panel of related N-glycan standards with individual proton NMR records and glycan structure diagrams.

Proton NMR and structure · N-glycan example 1 (1/4)

N-glycan standard panel · Proton NMR and structure · N-glycan example 1

N-glycan standard panel: Proton NMR and structure · N-glycan example 1

Four supplied N-glycan examples show different terminal motifs and branch arrangements. Each spectrum is paired with its own structure. Select standards by the complete structure and linkage pattern, and confirm the required specifications with our experts.

Selected project data. These panels are not a certificate for every product or batch. HPLC peak-area percentages are not an absolute purity measurement.

Case 06

Oligosaccharide standards

Proton NMR · Defined carbohydrate materials

Selected oligosaccharide reference materials with proton NMR characterization, including a sialyl Lewis X example.

Proton NMR · oligosaccharide example 1 (1/3)

Oligosaccharide standards · Proton NMR · oligosaccharide example 1

Oligosaccharide standards: Proton NMR · oligosaccharide example 1

The supplied records include two oligosaccharide panels and a separate sialyl Lewis X spectrum. NMR is the available method for these examples. Discuss any additional mass-spectrometric or chromatographic documentation needed for your application.

Selected project data. These panels are not a certificate for every product or batch. HPLC peak-area percentages are not an absolute purity measurement.

Project examples are shared anonymously. Quantities and specifications describe these projects; feasibility, purity, and scale are reviewed for each new request. Research Use Only.

This service is for Research Use Only, not intended for any clinical use.

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