α1,2-fucosyltransferase

α1,2-fucosyltransferase Accepted Name Type 1 galactoside alpha-(1,2)-fucosyltransferase. Alternative Name(s) Alpha-(1->2)-L-fucosyltransferase. Alpha-2-fucosyltransferase. Alpha-2-L-fucosyltransferase. Beta-galactoside alpha-1->2 fucosyltransferase. Blood group H alpha-2-fucosyltransferase. Blood-group substance H-dependent fucosyltransferase. Galactoside 2-alpha-L-fucosyltransferase. Guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase. Guanosine diphosphofucose-galactoside 2-L-fucosyltransferase. Guanosine diphosphofucose- galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L- fucosyltransferase. Guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase. Guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase. Secretor-type beta-galactoside alpha-1->2 fucosyltransferase. Reaction catalysed GDP-beta-L-fucose  +  beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R  <=>  GDP  +  alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R Comment(s) The enzyme acts on a glycoconjugates where the substituent group is a glycoprotein or glycosphingolipid. The recognized moiety of the substrate is known as a type 1 histo- blood group antigen precursor disaccharide, and the action of the enzyme produces an H type 1 antigen. The enzyme from the bacterium Helicobacter pylori cannot act on type 2 substrates (see EC  2.4.1.344 ).