UDP-6-azido-GlcNAc (UDP-6-N3-GlcNAc)

UDP-6-azido-GlcNAc carries an azido substitution at the sugar C6 position. The resulting handle can be detected using an appropriate click-chemistry partner after enzymatic transfer. It differs from UDP-GlcNAz, where the azide is part of the N-acyl group. Research context A published chemoenzymatic cell-surface labeling study used UDP-6-N3-GlcNAc with the N. meningitidis β1–3-N-acetylglucosaminyltransferase NmLgtA. This establishes a specific research example, not universal transferase compatibility. Product selection and documentation Reference identifiers describe the labelled chemical form; they do not establish the counterion or hydration of a particular lot. Confirm the supplied form, assay, purity method and storage conditions on the lot certificate of analysis. Use the lot-specific formula weight when preparing molar solutions. Experimental planning Enzyme acceptance depends on the transferase, acceptor and reaction conditions. Validate the donor with your enzyme system; nucleotide sugars should not be assumed to enter cells simply because related monosaccharide precursors do.